Mohanlal Sukhadia University was the first in Rajasthan to start Post-Graduate Program in Biotechnology in the year 1997 followed by a three year B.Sc. Biotechnology Course from the academic session 2005-2006. The department initially started functioning from the Department of Botany, University College of Science (old campus of the university), but is now located in a modern independent building complex “Vigyan Bhawan, Block B” in the new campus of the University.

The department boasts of an excellent infra-structure with aesthetically landscaped large lush green gardens that surround the building and provide a serene eco-friendly environment for the students. Separate UG and PG classrooms, fully equipped laboratories with latest state-of-the-art equipments, Central Instrumental Facility, Research laboratory, a separate Autoclave Zone, Inoculation facility and a Culture room impart rich theoretical knowledge along with hands on practical training in Plant Biotechnology, Molecular Biology, Microbiology and other related fields to the students.